Yonkeura 1987.

Methods	Randomised, double blind, 4 parallel groups. Single and multiple oral dose phases Medication administered when baseline pain reached a moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly to 6 hours
Participants	Episiotomy N = 218 All F Mean age 24 years
Interventions	Codeine 60 mg, n = 53 Meclofenamate 100 mg, n = 55 Meclofenamate 200 mg, n = 55 Placebo, n = 52
Outcomes	PI: standard 4 point scale PR: standard 5 point scale Use of rescue medication Adverse events Withdrawals
Notes	Oxford Qualtiy Score: R1, DB2, W1. Total = 4 Rescue medication allowed after 1 hour
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Not described
Allocation concealment?	Unclear risk	Not described
Blinding? All outcomes	Unclear risk	"identically appearing capsules"

DB ‐ double blind, N ‐ number of participants in study, n ‐ number of participants in treatment arm, PGE ‐ patient global evaluation, PI ‐ pain intensity, PR ‐ pain relief, R ‐ randomised, W ‐ withdrawals h ‐ hours, pts ‐ participants, mins ‐ minutes