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. 2014 Jul 1;9(13):1316–1322. doi: 10.4103/1673-5374.137580

Figure 1.

Figure 1

Thrombosis and thrombolysis pathways.

Thrombosis and thrombolysis are both important processes. Thrombosis is triggered by prothrombin activator, which causes formation of cross-linked polymer fibrin with the addition of Ca2+. Thrombolysis has a more complex feedback mechanism. Endogenous plasminogen is activated and converted to plasmin in the intravascular space by plasminogen activator, and the cross-linked polymer fibrin is degraded into soluble fibrin degradation products by plasmin and then cleared.