Protein expression of phosphorylated c-Jun N-terminal kinases (p-JNK) and phosphorylated c-Jun (p-c-Jun) in retinal ganglion cells (RGCs) and the lateral geniculate nucleus (LGN) of rats following laser treatment.
Western immunoblot and quantitative analysis of p-JNK and p-c-Jun in the RGCs (A, B) and LGN (A, C) in the damage control group at different time points. Three days after laser treatment, p-JNK and p-c-Jun proteins are mildly expressed in the RGCs and the LGN. The expression levels reach a peak at 7 days and are maintained at a high level. At each time point, the expression of p-JNK and p-c-Jun protein in the LGN increases af-ter laser treatment, reaches a peak at 14 days, and remains at a high level during the observation time. I–V: Before treatment, 3, 7, 14, 28 days after treatment in damage control group.