Table 1.
Patient characteristics
| All Solitaire SWIFT + STAR (n = 291) |
SWIFT randomized to Solitaire (n = 58) |
SWIFT randomized to Merci (n = 55) |
P value (Merci vs. Solitaire) |
|
|---|---|---|---|---|
| Age | 67·8 ± 12·6 | 67·1 ± 12·0 | 67·1 ± 12·1 | 0·99 |
| NIHSS | 17 (13–20) | 18 (14–19) | 18 (13–22) | 0·67 |
| HTN | 63·9% (186/291) | 72·4% (42/58) | 69·1% (38/55) | 0·84 |
| DM | 18·6% (54/291) | 24·1% (14/58) | 30·9% (17/55) | 0·53 |
| AF | 39·5% (115/291) | 44·8% (26/58) | 67·3% (37/55) | 0·02 |
| Female | 58·4% (170/291) | 51·7% (30/58) | 49·1% (27/55) | 0·85 |
| IV thrombolytics | 55·3% (161/291) | 32·8% (19/58) | 47·2% (25/55) | 0·17 |
| sICH | 1·4% (4/291) | 1·7% (1/58) | 10·9% (6/55) | 0·06 |
| Proximal clot | 86·5% (244/285) | 87·9% (51/58) | 77·4% (41/53) | 0·21 |
| THRIVE score | 4 (3–6) | 4·5 (3–6) | 5 (4–6) | 0·18 |
| HIAT score | 1 (1–2) | 1 (1–2) | 1 (1–2) | 0·94 |
| HIAT-2 score | 2 (2–4) | 2 (1–4) | 3 (2–4) | 0·25 |
| SPAN-100 | 8·1% (23/285) | 8·6% (5/58) | 7·3% (4/55) | 1·00 |
Categories in columns are All Solitaire = all patients in Solitaire run-in phase of SWIFT + all patients randomized to Solitaire in SWIFT RCT + all patients in STAR; SWIFT-Merci = all patients randomized to Merci in SWIFT RCT; SWIFT-Solitaire = all patients randomized to Solitaire in SWIFT RCT. Age is presented as mean ± SD. NIHSSand other ordinal scores are presented as median [interquartile range (IQR)]. Dichotomous values (comorbidities, gender, and SPAN-100) are presented as % (number out of total). Between the categories of SWIFT-Merci and SWIFT-Solitaire, continuous data were compared by the nonparametric Wilcoxon rank-sum test, and categorical data were compared by Fisher's exact test. IV thrombolytics = use of IV thrombolytics prior to the procedure. sICH = occurrence of symptomatic ICH within 24 h of the procedure. Proximal clot = occlusion of intracranial ICA, proximal MCA (M1 segment), basilar artery.
AF, atrial fibrillation; DM, diabetes mellitus; HIAT, Houston Intra-Arterial Therapy score; HTN, hypertension; ICA, internal carotid artery; ICH, intracerebral haemorrhage; IV, intravenous; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; RCT, randomized controlled trial; SD, standard deviation; sICH, symptomatic intracerebral haemorrhage; SPAN, Stroke Prognostication using Age and NIH Stroke Scale score; THRIVE, totaled health risks in vascular events.