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Predicted amino acid sequence of Enpp1ttw-Ham compared with the known human, mouse, and Enpp1ttw-Jic sequences, as shown. Enpp1ttw-Ham and Enpp1ttw-Jic mutations are Val63stop and Gly568stop, respectively. The amino acid sequence homology is 78.8% between mouse and human. The transmembrane region is boxed. Arrowheads indicate conserved cysteine residues. Asterisks indicate amino acid identity between human and mouse.
