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Quantitative real-time PCR determination of HAS1 (A), HAS2 (B), HAS3 (C), and PH20 (D) mRNA expression in brain homogenates of the control, craniotomy (sham CCI), contralateral CCI, and ipsilateral CCI hemisphere at 4 h, 24 h, 3 days, and 7 days post-CCI. Results are presented as the fold change relative to the control group (=1). *p < 0.05; **p < 0.01.
