Table 1.
Histopathological findings in the Sh instilled bladders and controls.
Group | n | W | N | U | I | L | M | D |
---|---|---|---|---|---|---|---|---|
Group 1 (Sh treated) | 10 | 20 | 7/10 (70%) | 5/10 (50%) | 9/10 (90%) | 9/10 (90%) | 0/10 (0%) | 3/10 (30%) |
Group 2 (Control) | 10 | 20 | 10/10 (100%) | 9/10 (90%) | 2/10 (20%) | 2/10 (20%) | 0/10 (0%) | 0/10 (0%) |
Group 3 (Sh treated) | 10 | 40 | 0/10 (0%) | 0/10 (0%) | 10/10 (100%) | 9/10 (90%) | 4/10 (40%) | 7/10a (70%) |
Group 4 (Control) | 10 | 40 | 10/10 (100%) | 10/10 (100%) | 3/10 (30%) | 3/10 (30%) | 0/10 (0%) | 0/10 (0%) |
n, number of animals; W, weeks between treatment and sacrifice; N, normal urothelium; U, presence of umbrella cells; I, inflammatory infiltrate; L, infiltration of lymphocyte; M, infiltration of mastocytes; D, dysplasia.
(p=0.001, Group 3 Vs. Group 4) (12).