Methods | R, DB, PC, parallel-group Four attacks treated. Medication (2 tablets) taken at onset of attack, repeated after 1 and 4 h if necessary (maximum 6 tablets in 24 h). Rescue medication (aspirin 600 mg) after 4 h if necessary |
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Participants | Common or classical migraine (≥ 2 years). Aged 20-50 years. Frequency 2 to 8 per month. Excluded: prophylactic treatment within 4 weeks N = 49 (42 completed 4 attacks) M 16, F 33 Mean age 33 years |
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Interventions | Paracetamol + metoclopramide 2 × 500/5 mg Placebo |
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Outcomes | Severity and duration of attacks Adverse events Withdrawals |
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Notes | Oxford Quality Score: R1, DB2, W1. Total = 4 | |
Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Unclear | Not described |
Allocation concealment? | Unclear | Not described |
Blinding? All outcomes |
Yes | “matched placebo” |