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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: J Immunol. 2008 Apr 1;180(7):4848–4857. doi: 10.4049/jimmunol.180.7.4848

Figure 3. Expanded gB-8p-specific memory cells in old HSV-1 infected mice uniformly exhibit central memory phenotype.

Figure 3

Splenocytes (shown) or lymphocytes isolated from blood (not shown) from old HSV-1 infected mice with age-related expansions of gB-8p-specific memory CD8+ T-cells were stained with CD8, tetramer and a panel of surface markers (CD44, CD62L, Ly6C, CD127, CD122, CD43, CD27). The staining of tetramer+ (top panel) and tetramer- (bottom panel) CD8+ T-cells from a representative mouse is shown. The same phenotype was observed in CD8+ T-cells isolated from blood (not shown).