Table 2.
Disease-free survival analysis (Multivariate Cox model) of miR-34b/c methylation in 140 early stage lung AC patients.
Covariates in the model | Hazard Ratio |
95% confidence interval |
P-value | |
---|---|---|---|---|
Age, continuous | 1.02 | 0.994 – 1.05 | ns | |
Gender | Female | 1.00 | - | |
Male | 1.17 | 0.72 – 1.92 | ns | |
Stage | Stage I | 1.00 | - | |
Stage II | 2.73 | 1.69 – 4.40 | <0.001 | |
miR-34b/c | Low to medium | 1.00 | - | |
methylation | High (AUC > 1.34) | 2.16 | 1.32 – 3.52 | 0.002 |