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. Author manuscript; available in PMC: 2015 Mar 27.
Published in final edited form as: Cell. 2014 Mar 27;157(1):41–50. doi: 10.1016/j.cell.2014.02.013

Figure 5. Niche as an interlocutor of organismal needs.

Figure 5

How the niche must incorporate signals indicating the state of the tissue and organism to properly regulate cell production under homeostatic and stress conditions.