A) Bio inhibition of GSK3β blocked Y216 phosphorylation and B) GSK3β siRNA knockdown. C) increased CSPC proliferation. D) β-Catenin siRNA, 100 nM, knockdown decreased levels to 20% of scrambled siRNA. E) β-Catenin knockdown increased levels of CSPC proliferation in cells treated with and without 25 nM SDF1 for 24 hours. Values are the mean ± SE, n=2-4. * p<0.05, ** p<0.01 vs Veh or Scr siR, †† p<0.01 vs treated control.