FIG 1 .
Primary-structure representation of the YopM isoforms and variants used in this study. Representations of YopM32777, YopMKIM, and three deletion variants of the KIM isoform are shown. N-terminal and C-terminal regions enclosed by dashed lines indicate the highest conservation between YopM32777 and YopMKIM, as determined by sequence alignment with ClustalW (see Fig. S1 in the supplemental material). The N-terminal gray rectangles correspond to the two α-helices, LRRs are represented by numbered boxes, and the conserved C-terminal tail is shown as a gray rectangle. Colored shading of boxes is used to indicate that additional LRRs in YopM32777 are assigned numbers as subrepeats of LRRs 3, 5, and 7 of YopMKIM. The positions of the YLTD motif in LRR 10 of YopMKIM and the corresponding DLTD motif in LRR 10 of YopM32777 are shown.