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H&E-stained sections of lungs from mice inoculated intranasally with 2.5 × 105 yeast cells. Sections of lungs from mice infected with G186A, G217B, and WU24 were analyzed 8, 12, 16, 20, and 32 days postinoculation. Representative sections of the Histoplasma-infected lungs are shown. The G217B strain caused more noticeable lung damage than did either the G186A or WU24 strains in mice infected using a high sublethal dose.
