FIG 6 .

Antibacterial effect of PVP-SE1gp146 and PCNP-PVP-SE1gp146 (LoGT-008) in a P. aeruginosa PA14-infected human keratinocyte monolayer. A mixture of 2 µM of PVP-SE1gp146/LoGT-008 and 0.005 mM of EDTA was applied to a 5-day-old confluent keratinocyte monolayer that was infected with 10⁵ CFU/ml (A) or 10⁷ CFU/ml (B) P. aeruginosa PA14 1 h before treatment. Numbers of surviving bacteria (squares) and surviving keratinocytes (bars) were quantified after 4 h of infection. Proportions of surviving bacteria are shown relative to the infected, untreated control results. Significantly different conditions (P < 0.05) are indicated with bold (keratinocyte survival) or italic (bacterial survival) letters.