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. 2014 Jul 15;5(4):e01188-14. doi: 10.1128/mBio.01188-14

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Copyright © 2014 Dou et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 6 — Parasites deficient in CPL and GRA2 are virulence attenuated. (A) CPL and GRA2 contribute synergistically to virulence. One thousand parasites of each strain were used to infect outbred CD-1 mice by subcutaneous injection. Data are combined from two independent experiments, each with 5 mice per group. (B) Pru strain parasites deficient in CPL are virulence attenuated. The indicated doses of PruΔku80LUC and PruΔku80LUCΔcpl parasites were injected into C57BL/6 mice intraperitoneally. Data are combined from two independent experiments, each with 5 mice per group.