Figure 8. DNA/Ad and AdCA: Comparison of positive T cell activities and per cent of total activities to AMA1 peptide pools.

ELISpot IFN-γ, CD8+ T cell IFN-γ, and CD8+ T cell EM IFN-γ activities to individual AMA1 peptide pools (Ap8 and Ap10) were calculated as per cent of total activities of summed responses to all AMA1 peptide pools. All volunteers positive with Ap8 or Ap10 were selected. Panels A, B, C: Ap8: protected v10 and v18 had lower activities than one or more AdCA volunteers, but highest per cent activities; v194 (delay to patency, blue arrows) had higher per cent ELISpot and CD8+ T cell IFN-γ activities than other AdCA volunteers, but no CD8+ T cell IFN-γ EM activity. Panels D, E, F: Ap10: protected v11 had highest per cent ELISpot, CD8+ T cell IFN-γ and CD8+ T cell IFN-γ EM activities to Ap10.