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. 2014 Sep 11;9(9):e106241. doi: 10.1371/journal.pone.0106241

Table 2. ELISpot responses to Ap8 and Ap10 peptide pools and individual 15mer peptides within each pool.

Pool 15mer Sequence v102 v111 v182 V1563 V1943
Prot. Prot. Prot. NP Delay
Ap8 193 321 141 47
A92 EGFKNKNASMIKSAF 1 0 0 4
A93 NKNASMIKSAFLPTG 0 2 0 4
A94 SMIKSAFLPTGAFKA 9 10 11 6
A95 SAFLPTGAFK ADRYK 9 2 61 4
A96 PTGAFKADRYKSHGK 1 2 0 3
A97 FKADRYKSHGKGYNW 164 270 141 48
A98 RYKSHGKGYNW GNYN 96 85 14 7
A99 HGKGYNWGNYNTETQ 0 5 5 6
A100 YNWGNYNTETQKCEI 1 5 0 6
A101 NYNTETQKCEIFNVK 0 0 1 0
A102 ETQKCEIFNVKPTCL 0 0 0 6
A103 CEIFNVKPTCLINNS 1 0 1 1
A104 NVKPTCLINNSSYIA 3 0 0 0
Ap10 159
A118 EGNKKIIAPRIFISD 2
A119 KIIAPRIFISDDKDS 0
A120 PRIFISDDKDSLKCP 1
A121 ISDDKDSLKCPCDPE 3
A122 KDSLKCPCDPEMVSN 2
A123 KCPCDPEMVSNSTCR 1
A124 DPEMVSNSTCRFFVC 0
A125 VSNSTCRFFVCK CVE 140
A126 TCRFFVCKCVERRAE 9
A127 FVCKCVERRAEVTSN 4
A128 CVERRAEVTSNNEVV 10
A129 RAEVTSNNEVVVKEE 0
A130 TSNNEVVVKEEYKDE 0
1

DNA/Ad cells collected 28 days after malaria challenge;

2

DNA/Ad cells collected 84 days after malaria challenge.

3

AdCA cells collected 2 months after the malaria challenge. Prot.  =  Protected. NP = Not Protected. All 15mer peptides within Ap8 and Ap10 were tested with DNA/Ad, and AdCA-immunized volunteers in ELISpot assays. Positive activities (bold): activity was greater than twice that of control, and the difference in absolute count was >10 sfc/m. Predicted epitopes within positive 15mers are shown in bold and underlined.