Table 2. Weight variations in treatment groups during comparative efficacy study of OlPC in L. major infected BALB/c mice.
Day | Vehicle control | %1 | fluconazole | % | miltefosine | % | OlPC | % | amphoB | % |
Baseline | 22.8±0.4 | 23.1±0.5 | 24.2±0.7 | 22.6±0.3 | 22.7±0.3 | |||||
n = 6 | n = 6 | n = 6 | n = 6 | n = 6 | ||||||
4 | 22.3±0.3 | −2.2 | 22.4±0.3 | −3.0 | 22.0±0.6 | −9.3 | 21.5±0.5 | −4.9 | 22.3±0.3 | −1.8 |
n = 6 | n = 6 | n = 6 | n = 6 | n = 6 | ||||||
10 | 21.2±0.3 | −7.1 | 21.2±0.3 | −8.2 | 20.6±0.2 | −14.9 | 21.7±0.4 | −4.0 | 21.1±0.5 | −7.1 |
n = 6 | n = 6 | n = 6 | n = 6 | n = 6 | ||||||
13 | 21.1±0.4 | −7.5 | 20.8±0.4 | −10.0 | 19.3±0.8 | −20.6 | 21.0±0.8 | −6.9 | 23.1±0.2 | +2.0 |
n = 6 | n = 6 | n = 4 | n = 5 | n = 6 | ||||||
27 | 21.3±0.5 | −6.4 | 20.7±0.4 | −10.4 | 22.0±1.0 | −9.1 | 21.6±0.7 | −4.5 | 23.4±0.4 | +2.9 |
n = 6 | n = 5 | n = 3 | n = 3 | n = 6 | ||||||
34 | 20.8±0.7 | −8.9 | 20.0±0.4 | −13.4 | 21.6±0.1 | −11.0 | 23.7±0.6 | +5.0 | 23.0±0.4 | +1.5 |
n = 52 | n = 5 | n = 3 | n = 3 | n = 6 |
% compared to baseline weight;
No weight available for mouse #584 on Day 34.