Table 2. Effects of dobutamine (DOB) or vehicle (VEH) administration during hindlimb unloading (HU) or ambulatory cage activity (CC) on metaphyseal bone mass and geometry at the distal femur as measured by ex vivo pQCT scans.

	CC		HU
	VEH	DOB	VEH	DOB
Total BMC (mg)	12.19±0.42	12.03±0.29	10.10±0.25b	10.87±0.27a ,c
Total Bone Area (mm2)	20.61±0.76	20.25±0.40	19.18±0.61	20.49±0.54
Total vBMD (mg/cm3)	593.33±11.33	595.20±11.58	531.02±16.39b	533.32±11.26c
Cancellous vBMD (mg/cm3)	329.29±15.27	320.25±12.12	245.96±7.77b	271.85±6.50a ,c

^aHU+DOB vs. HU+VEH (p≤0.05); ^bHU+VEH vs. CC+VEH (p≤0.05); ^cHU+DOB vs. CC+DOB (p≤0.05).