Table 1. Expression of genes of interest in Arhgap28del bone tissues.
Gene | Gene symbol | wild type | Arhgap28del | Fold change | q value |
RhoGAP genes | |||||
Arhgap28 | Arhgap28 | 271.7 | 110.3 | −2.5 | 0.037 |
82.5 | 76.5 | −1.1 | 0.345 | ||
67.1 | 64.2 | −1 | 0.466 | ||
Arhgap6 | Arhgap6 | 62.2 | 62.1 | −1 | 0.656 |
271.4 | 275.8 | 1 | 0.607 | ||
20.2 | 24.7 | 1.2 | 0.257 | ||
Arhgap18 | Arhgap18 | 488.6 | 397.5 | −1.2 | 0.106 |
82.2 | 73.2 | −1.1 | 0.356 | ||
Deleted in liver cancer 1 | DLC1 | 48.6 | 52.3 | 1.1 | 0.413 |
Rho GTPases genes | |||||
RhoA | RhoA | 5112.5 | 5060.3 | −1 | 0.627 |
4777.4 | 4752.9 | −1 | 0.643 | ||
12.9 | 16.3 | 1.3 | 0.099 | ||
Rac1 | Rac1 | 3672.1 | 3349.2 | −1.1 | 0.254 |
3591.8 | 3611.5 | 1 | 0.645 | ||
14.5 | 18.0 | 1.2 | 0.085 | ||
Cdc42 | Cdc42 | 239.8 | 190.0 | −1.3 | 0.197 |
4229.0 | 3745.1 | −1.1 | 0.191 | ||
3386.3 | 3059.5 | −1.1 | 0.352 | ||
8834.9 | 8114.0 | −1.1 | 0.27 | ||
RhoQ | RhoQ | 2126.4 | 2001.0 | −1.1 | 0.52 |
actin genes | |||||
alpha-skeletal actin | Acta1 | 334.1 | 94.0 | −3.6 | 0.015 |
alpha-cardiac-actin | Actc1 | 687.1 | 223.8 | −3.1 | 0.046 |
bone collagen genes | |||||
collagen, type I, alpha 1 | Col1a1 | 10217.8 | 10997.6 | 1.1 | 0.413 |
10473.8 | 11427.3 | 1.1 | 0.528 | ||
collagen, type I, alpha 2 | Coll1a2 | 321.6 | 767.0 | 2.4 | 0.163 |
23205.8 | 24471.2 | 1.1 | 0.422 | ||
19122.7 | 1024.8 | 1.1 | 0.444 | ||
collagen, type X, alpha 1 | Col10a1 | 1917.6 | 1024.8 | −1.9 | 0.056 |
Comparison of gene expression in wild type and Arhgap28del bone tissues. Mean intensities from hybridization of triplicate samples to probe set(s) for the genes listed.