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. 2014 Sep 11;9(9):e107133. doi: 10.1371/journal.pone.0107133

Table 2. UCB-stem cell Class B (Profile-2) transcription factors.

Gene No. GENE SYMBOL ENRICHMENT SCORE1 GENE RANK2
1 SON −0.05842792 2994
2 TSC22D3 −0.058295283 2927
3 NFX1 −0.054407794 2935
4 DMC1 −0.053078525 2844
5 ATF3 −0.051295283 2927
6 TRIM22 −0.04250992 3495
7 SOX6 −0.04150992 3495
8 NFKB2 −0.038754087 2935
9 BATF −0.03710674 3189
10 GATA1 −0.03329886 3749
11 KLF1 −0.032754087 2935
12 FOXC1 −0.030511508 3262
13 SP140 −0.03033415 3212
14 STAT1 −0.02901836 3336
15 MAFB −0.02863797 3306
16 GLI2 −0.02699749 3520
17 BCL6 −0.02135538 2685
18 ZNF256 −0.0191952 2182
19 SYCP1 −0.017439079 3545
20 CDT1 −0.017186195 2181
21 E2F1 −0.013077641 2999
22 MXI1 −0.012244189 3349
23 IKZF4 −0.008271581 2442
24 HMGA1 −0.007992041 2911
25 CREB1 −0.006540393 2653
26 JUN −0.005443786 3064
27 OLIG2 −0.003412304 3554
28 SIAH2 −0.002095686 3614
29 HSF1 −0.001728075 2562
30 ZHX2 −0.00001730 2292
1

ES, enrichment score of TFs identified by GSEA using three TF gene sets (TF activity, TF complex and DNA binding). A negative ES indicates genes with a negative correlation to Profile-1 (i.e. Profile-2 gene with increased expression from day 21 to day 56).

2

Gene Rank, gene rank list generated by GSEA using 3786 TFs with >1.5-fold changes in expression from day 21 to day 56 in culture.