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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Regen Med. 2014 Jul;9(4):437–452. doi: 10.2217/rme.14.26

Figure 6. Human biomarkers of apoptosis, proliferation and neural commitment.

Figure 6

(A) c-PARP and (B) CyclinB1 antibodies are biomarkers detecting cell death and proliferation in human spleen, which do not cross-react with (C–E) mouse or (D–F) rat spleens. (G) Fifteen days post-transplantation of human neural precursor cells, these detected cells undergoing apoptosis or (H) clusters of proliferating human cells into the rat spinal cord tissue. (I) Neural precursor cells express nestin at 1-day postinjection and (J) later on become progressively immunoreactive for a human-specific neuron-specific enolase antibody. Scale bar represents 50 μm.