. Author manuscript; available in PMC: 2014 Sep 11.

Published in final edited form as: Cochrane Database Syst Rev. 2012 Mar 14;3:CD004233. doi: 10.1002/14651858.CD004233.pub3

Comparison 1. Celecoxib 200 mg versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 At least 50% pain relief over 4-6 hours	4	705	Risk Ratio (M-H, Fixed, 95% CI)	3.49 [2.40, 5.06]
1.1 Dental pain	3	423	Risk Ratio (M-H, Fixed, 95% CI)	15.86 [5.14, 48.99]
1.2 Postsurgical pain	1	282	Risk Ratio (M-H, Fixed, 95% CI)	1.83 [1.26, 2.68]
2 Use of rescue medication over 24 hours	2	271	Risk Ratio (IV, Fixed, 95% CI)	0.78 [0.70, 0.86]
3 Any adverse event	4	669	Risk Ratio (M-H, Fixed, 95% CI)	0.90 [0.63, 1.29]
3.1 Dental	3	387	Risk Ratio (M-H, Fixed, 95% CI)	0.97 [0.63, 1.49]
3.2 Orthopaedic	1	282	Risk Ratio (M-H, Fixed, 95% CI)	0.8 [0.43, 1.48]