Table 2A.
Treatment of apo E-/- mice with G-CSF resulted in significantly larger lumen areas, smaller plaque areas, and smaller percent plaque areas compared with control mice treated with vehicle only
| EEL (mm2) | IEL (mm2) | Lumen (mm2) | Plaque (mm2) | Plaque Area (%) | |
|---|---|---|---|---|---|
| Control | 0.181 ± 0.068 | 0.148 ± 0.067 | 0.090 ± 0.032 | 0.058 ± 0.005 | 63.7 ± 18.3 |
| G-CSF | 0.268 ± 0.087 | 0.213 ± 0.075 | 0.174 ± 0.069* | 0.039 ± 0.014* | 41.5 ± 2.9** |
EEL = area within the external elastic lamina; IEL = area within the internal elastic lamina; Lumen = area of the lumen; Plaque = area of plaque (IEL-Lumen); Plaque % Area = (plaque area/[EEL-Lumen Area]).
*
p < 0.05;
**
p < 0.01 (G-CSF vs. control).