Table 2.
Univariate analyses in patients with ESCC
| Cases (n, %) | OS (%) | HR (95% CI) | P-value | |
|---|---|---|---|---|
| Age (years) | 0.453 | |||
| ≤ 60 | 279 (56.3) | 44.4 | 1.000 | |
| > 60 | 217 (43.7) | 41.0 | 1.093 (0.865-1.381) | |
| Gender | 0.079 | |||
| Female | 70 (14.1) | 51.4 | 1.000 | |
| Male | 426 (85.9) | 41.5 | 1.373 (0.959-1.965) | |
| Tumor length (cm) | < 0.001 | |||
| ≤ 3 | 143 (28.8) | 61.5 | 1.000 | |
| > 3 | 353 (71.2) | 35.4 | 2.056 (1.531-2.761) | |
| Tumor location | 0.249 | |||
| Upper/Middle | 272 (54.8) | 46.3 | 1.000 | |
| Lower | 224 (45.2) | 38.8 | 1.146 (0.907-1.447) | |
| Vessel involvement | 0.004 | |||
| Negative | 407 (82.2) | 45.7 | 1.000 | |
| Positive | 89 (17.8) | 30.3 | 1.415 (1.067-1.876) | |
| Differentiation | 0.021 | |||
| Well/Moderate | 407 (82.2) | 44.5 | 1.000 | |
| Poor | 89 (17.8) | 36.0 | 1.403 (1.049-1.878) | |
| ABO blood group | 0.043 | |||
| Non-O group | 311 (62.7) | 45.7 | 1.000 | |
| O group | 185 (37.3) | 38.4 | 1.275 (1.005-1.617) | |
| T grade | < 0.001 | |||
| T1-2 | 173 (34.9) | 61.3 | 1.000 | |
| T3-4a | 323 (65.1) | 33.1 | 2.135 (1.623-2.810) | |
| N staging | < 0.001 | |||
| N0 | 283 (57.6) | 61.1 | 1.000 | |
| N1-3 | 213 (42.4) | 18.8 | 2.965 (2.331-3.772) | |
| Adjuvant therapy | 0.097 | |||
| No | 361 (72.8) | 45.7 | 1.000 | |
| Yes | 135 (27.2) | 35.6 | 1.236 (0.960-1.591) |
ESCC, esophageal squamous cell carcinoma; OS, overall survival; HR, hazard ratio; CI, confidence interval.