Table 2.
Patients’ parametric changes during induction of anesthesia
| Group | OAA/S | |||||
|---|---|---|---|---|---|---|
|
|
||||||
| 5 | 4 | 3 | 2 | 1 | ||
| Time (s) | PH | 0 | 274.3 ± 68.7 | 387.5 ± 78.6* | 514.4 ± 97.6 | 618.4 ± 72.0* |
| NS | 0 | 303.3 ± 73.3 | 483.9 ± 78.5 | 566.2 ± 90.0 | 683.1 ± 87.9 | |
| Dose of propofol (mg/kg) | PH | 0 | 0.66 ± 0.21 | 1.04 ± 0.25* | 1.46 ± 0.34 | 1.83 ± 0.24* |
| NS | 0 | 0.77 ± 0.20 | 1.29 ± 0.26 | 1.66 ± 0.3 | 2.05 ± 0.31 | |
| Ce of propofol (μg/ml) | PH | 0 | 0.81 ± 0.24 | 1.31 ± 0.27* | 1.77 ± 0.35* | 2.18 ± 0.29* |
| NS | 0 | 0.97 ± 0.26 | 1.61 ± 0.27 | 2.00 ± 0.32 | 2.42 ± 0.30 | |
| BIS | PH | 97.3 ± 1.1 | 92.5 ± 5.7 | 81.5 ± 5.5 | 77.5 ± 3.4 | 71.1 ± 10.8 |
| NS | 97.7 ± 0.6 | 90.6 ± 6.3 | 80.0 ± 6.1 | 73.8 ± 6.4 | 67.4 ± 7.2 | |
| MAP (mmHg) | PH | 82.6 ± 9.7 | 79.7 ± 8.5 | 75.2 ± 7.6 | 74.3 ± 7.9 | 73.9 ± 9.5 |
| NS | 84.3 ± 7.9 | 76.3 ± 7.5 | 73.4 ± 7.0 | 71.3 ± 6.3 | 70.4 ± 7.2 | |
| HR (bpm) | PH | 76.7 ± 13.2 | 74.7 ± 11.7 | 74.7 ± 10.6 | 73.1 ± 11.1 | 73.6 ± 12.1 |
| NS | 76.2 ± 13.2 | 72.1 ± 11.5 | 71.5 ± 9.5 | 72.9 ± 10.1 | 72.4 ± 10.4 | |
| RPP | PH | 9283 ± 2220 | 8443 ± 1828 | 8043 ± 1482 | 7431 ± 2228 | 7525 ± 1567 |
| NS | 9384 ± 1888 | 7964 ± 1342 | 7569 ± 1159 | 7626 ± 1269 | 7388 ± 1350 | |
Values are mean ± SD.
*
p < 0.05 compared with Group NS.
OAA/S = Observer’s Assessment of Alertness / Sedation rating scale; Ce = effect-site concentration; BIS = Bispectral Index; MAP = mean arterial pressure; HR =heart rate; RPP = rate-pressure product.