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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2006 Aug 4;291(6):L1256–L1266. doi: 10.1152/ajplung.00079.2006

Figure 2. Effect of lymphocyte subsets on lung function during PcP in IRD mice.

Figure 2

Pulmonary function testing was carried out on Pc-infected IRD mice at 9, 14, 21 and 28 days post-immune reconstitution. Lung compliance (Panel A), and resistance (Panel B) measurements were taken on non-depleted (closed circles), CD4-depleted (open circles) and CD8-depleted (closed triangles) IRD mice. Panel C shows PMN numbers in the BAL fluid of experimental mice, and Panel D shows Pneumocystis carinii-burden expressed as Log10(kexin DNA copies) as measured by quantitative real time PCR. The results were pooled data from three independent experiments, and each data point is the arithmetic mean ± 1 SEM (n= 8-16 mice for all groups at all time points except CD4-depleted mice at day 21 (n= 3). *P<0.05 as compared to non-depleted IRD mice.