Table 1. ALSPAC: The effect of CHRNA5 rs16969968^a on the trajectory of smoking quantity during pregnancy is moderated by partner smoking (n=1856).

Predictor	B	95% Confidence Interval		P value

		Lower Bound	Upper Bound
Model 1
Age	-0.0029	-.047	.041	0.90
Time	-.53	-.55	-.50	<0.0001
Partner smoking	0.23	0.19	0.29	<0.0001
rs16969968^a	.070	.033	0.11	1.8×10^-4

Model 2
Age	-0.0030	-0.047	0.041	0.90
Time	-0.51	-0.56	-0.46	<0.0001
Partner smoking	0.16	0.082	0.24	<0.0001
rs16969968^a	0.078	0.021	0.14	7.8×10^-3
rs16969968^a * Time	0.017	-0.032	0.066	0.50
Partner smoking* Time	0.032	-0.10	0.04	0.38
Partner smoking* rs16969968^a * Time^a	0.071	0.013	0.13	0.017

rs1051730 was used as the proxy for rs16969968 (r²=1.0 in 1000G CEU).

Table 1. ALSPAC: The effect of CHRNA5 rs16969968a on the trajectory of smoking quantity during pregnancy is moderated by partner smoking (n=1856).