Table 3b.

Estimated Rate Ratios of Number of Diabetes Drug Classes in the Year Following Diabetes Diagnosis

Independent Variables	RR	95% CI	p
Year of Cohort Entry (ref: 2005)
2006	1.03	1.01–1.05	0.001
2007	1.03	1.01–1.05	0.010
2008	1.05	1.02–1.07	<.001
2009	1.07	1.05–1.09	<.001
Female	1.01	0.99–1.02	0.098
Age (ref: 60–69)
20–29	1.39	1.33–1.45	<.001
30–39	1.31	1.27–1.34	<.001
40–49	1.25	1.22–1.27	<.001
50–59	1.17	1.15–1.18	<.001
70–79	0.78	0.76–0.80	<.001
80–89	0.59	0.57–0.62	<.001
90+	0.44	0.39–0.50	<.001
Race/Ethnicity (ref: White)
Hispanic	1.04	1.02–1.05	<.001
Unknown	0.99	0.97–1.01	0.303
Black	1.07	1.05–1.09	<.001
Hawaiian/Pacific Islander	1.08	1.01–1.16	0.023
Asian	0.95	0.93–0.97	<.001
Native American	1.12	1.01–1.23	0.029
More than 1 Race	0.99	0.95–1.04	0.639
A1c Closest & Prior to Cohort Entry (ref: <6.5%)
6.5–6.9%	1.21	1.18–1.25	<.001
7.0–7.4%	2.34	2.27–2.41	<.001
7.5–7.9%	3.28	3.18–3.39	<.001
8.0–8.4%	3.77	3.64–3.91	<.001
8.5–8.9%	4.15	4.00–4.31	<.001
>=9.0%	5.21	5.08–5.33	<.001
Missing	2.74	2.68–2.80	<.001
History of Depression	1.06	1.04–1.09	<.001
History of Hypertension	0.97	0.96–0.98	<.001
History of Hyperlipidemia	0.90	0.89–0.92	<.001
History of Chronic Renal Disease (Stage 3, 4)	0.82	0.79–0.87	<.001
History of End Stage Renal Disease	0.53	0.47–0.59	<.001
Body Mass Index (ref: Normal)
Missing	0.94	0.92–0.97	<.001
Underweight (<18.5)	0.97	0.87–1.09	0.388
Overweight (>24.9–29.9)	1.01	0.98–1.03	0.572
Obese Level 1(>29.9–34.5)	1.01	0.99–1.04	0.283
Obese Level 2(>34.5–39.9)	1.05	1.02–1.08	0.001
Obese Level 3(>39.9)	1.10	1.07–1.13	0.033

Notes: (1) RR = Rate Ratio, CI = Confidence Interval, (2) model includes site fixed effects, (3) n=196,654