Skip to main content
. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2014 Apr 30;17(10):1549–1556. doi: 10.1017/S1461145714000510

Table 2.

Results from Multilevel Linear Regressions

Drinking Level
Block Predictor B SE p 95% CI
1 Diary Day −0.021 0.003 <0.001 −0.026 −0.016
Sex 0.546 0.314 0.085 −0.076 1.168
Baseline Heavy Drinking 3.067 0.574 <0.001 1.931 4.203
Medication Group −0.547 0.306 0.076 −1.153 0.059
Genotype Group −0.221 0.312 0.481 −0.838 0.397
2 Diary Day × Genotype Group −0.005 0.005 0.330 −0.015 0.005
Diary Day × Medication Group −0.008 0.005 0.122 −0.018 0.002
Medication Group × Genotype Group −1.506 0.612 0.015 −2.719 −0.293
3 Diary Day × Medication Group × Genotype Group −0.007 0.010 0.485 −0.028 0.013
Positive Alcohol Expectancies
Block Predictor B SE p 95% CI
1 Diary Day −0.007 0.001 <0.001 −0.009 −0.005
Sex 0.418 0.150 0.005 0.129 0.707
Medication Group −0.072 0.143 0.616 −0.354 0.211
Genotype Group 0.181 0.143 0.209 −0.103 0.467
2 Diary Day × Genotype Group −0.001 0.002 0.772 −0.005 0.003
Diary Day × Medication Group −0.004 0.002 0.030 −0.008 −0.001
Medication Group × Genotype Group −0.401 0.290 0.170 −0.980 0.173
3 Diary Day × Medication Group × Genotype Group −0.008 0.004 0.040 −0.016 −0.001
Desire to Drink
1 Diary Day −0.007 0.001 <0.001 −0.009 −0.005
Sex 0.073 0.116 0.528 −0.156 0.302
Medication Group −0.161 0.113 0.156 −0.384 0.062
Genotype Group 0.007 0.114 0.949 −0.218 0.233
2 Diary Day × Genotype group −0.002 0.002 0.504 −0.006 0.003
Diary Day × Medication group −0.004 0.002 0.110 −0.008 0.001
Medication group × Genotype group −0.040 0.231 0.862 −0.497 0.417
3 Diary Day × Medication group × Genotype Group −0.009 0.004 0.050 −0.018 −0.000

Note: Diary day (coded 1-84), Sex (coded 0=female, 1=male), Medication Group (coded 0=placebo, 1=topiramate) and Genotype Group (coded 0=A-allele carrier, 1=C-allele homozygote); Baseline Heavy Drinking=proportion of heavy drinking days during the 90 days prior to treatment.

Note: Diary day (coded 1-84), Sex (coded 0=female, 1=male), Medication Group (coded 0=placebo, 1=topiramate) and Genotype Group (coded 0=A-allele carrier, 1=C-allele homozygote); Baseline Heavy Drinking=proportion of heavy drinking days during the 90 days prior to treatment.