Table 2.
Drinking Level | ||||||
---|---|---|---|---|---|---|
Block | Predictor | B | SE | p | 95% CI | |
1 | Diary Day | −0.021 | 0.003 | <0.001 | −0.026 | −0.016 |
Sex | 0.546 | 0.314 | 0.085 | −0.076 | 1.168 | |
Baseline Heavy Drinking | 3.067 | 0.574 | <0.001 | 1.931 | 4.203 | |
Medication Group | −0.547 | 0.306 | 0.076 | −1.153 | 0.059 | |
Genotype Group | −0.221 | 0.312 | 0.481 | −0.838 | 0.397 | |
2 | Diary Day × Genotype Group | −0.005 | 0.005 | 0.330 | −0.015 | 0.005 |
Diary Day × Medication Group | −0.008 | 0.005 | 0.122 | −0.018 | 0.002 | |
Medication Group × Genotype Group | −1.506 | 0.612 | 0.015 | −2.719 | −0.293 | |
3 | Diary Day × Medication Group × Genotype Group | −0.007 | 0.010 | 0.485 | −0.028 | 0.013 |
Positive Alcohol Expectancies | ||||||
---|---|---|---|---|---|---|
Block | Predictor | B | SE | p | 95% CI | |
1 | Diary Day | −0.007 | 0.001 | <0.001 | −0.009 | −0.005 |
Sex | 0.418 | 0.150 | 0.005 | 0.129 | 0.707 | |
Medication Group | −0.072 | 0.143 | 0.616 | −0.354 | 0.211 | |
Genotype Group | 0.181 | 0.143 | 0.209 | −0.103 | 0.467 | |
2 | Diary Day × Genotype Group | −0.001 | 0.002 | 0.772 | −0.005 | 0.003 |
Diary Day × Medication Group | −0.004 | 0.002 | 0.030 | −0.008 | −0.001 | |
Medication Group × Genotype Group | −0.401 | 0.290 | 0.170 | −0.980 | 0.173 | |
3 | Diary Day × Medication Group × Genotype Group | −0.008 | 0.004 | 0.040 | −0.016 | −0.001 |
Desire to Drink | ||||||
---|---|---|---|---|---|---|
1 | Diary Day | −0.007 | 0.001 | <0.001 | −0.009 | −0.005 |
Sex | 0.073 | 0.116 | 0.528 | −0.156 | 0.302 | |
Medication Group | −0.161 | 0.113 | 0.156 | −0.384 | 0.062 | |
Genotype Group | 0.007 | 0.114 | 0.949 | −0.218 | 0.233 | |
2 | Diary Day × Genotype group | −0.002 | 0.002 | 0.504 | −0.006 | 0.003 |
Diary Day × Medication group | −0.004 | 0.002 | 0.110 | −0.008 | 0.001 | |
Medication group × Genotype group | −0.040 | 0.231 | 0.862 | −0.497 | 0.417 | |
3 | Diary Day × Medication group × Genotype Group | −0.009 | 0.004 | 0.050 | −0.018 | −0.000 |
Note: Diary day (coded 1-84), Sex (coded 0=female, 1=male), Medication Group (coded 0=placebo, 1=topiramate) and Genotype Group (coded 0=A-allele carrier, 1=C-allele homozygote); Baseline Heavy Drinking=proportion of heavy drinking days during the 90 days prior to treatment.
Note: Diary day (coded 1-84), Sex (coded 0=female, 1=male), Medication Group (coded 0=placebo, 1=topiramate) and Genotype Group (coded 0=A-allele carrier, 1=C-allele homozygote); Baseline Heavy Drinking=proportion of heavy drinking days during the 90 days prior to treatment.