(A) Voltage clamp recordings (holding potential = −72 mV) from an On-SAC froma Cx36 KO mousein control conditions (top) and following adaptation (bottom).
(B) Voltage clamp recordings (holding potential = −72 mV) from an On-SAC following adaption in control conditions (top) and in the presence of the gap junction antagonist MFA (bottom).
(C) The excitatory charge transfer during light onset (yellow) and light offset (grey) in individual On-SACs (circles) from Cx36KO retinas before (KO) and after (KO adapted) adaptation; and from WT retinas after adaptation in the presence of 100 μM meclofenamic acid (MFA adapted). Error bars = SD.
See also Figure S5.