Table 4.
Results and performance of the five diagnostic assays for cutaneous leishmaniasis
| Diagnostic method | Number of positives | True positives | Number of negatives | True negatives | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | χ ± [SE] |
|---|---|---|---|---|---|---|---|---|---|
| Direct examination | 19 | 19 | 39 | 14 | 43 | 100 | 100 | 36 | 0.270 ± 0.110 |
| Culture | 13 | 13 | 45 | 14 | 29 | 100 | 100 | 31 | 0.170 ± 0.102 |
| 13A/13B PCR | 48 | 44 | 10 | 10 | 100 | 71 | 92 | 100 | 0.791 ± 0.101 |
| Lmj4/Uni21 PCR | 35 | 35 | 23 | 14 | 79 | 100 | 100 | 61 | 0.652 ± 0.106 |
| ITS1-PCR | 45 | 44 | 13 | 13 | 100 | 93 | 98 | 100 | 0.950 ± 0.040 |
| PCR c | 44 | 44 | 14 | 14 | 100 | 100 | 100 | 100 | |
| Total | 44 | 14 |
PPV: Positive Predictive Value; NPV: Negative Predictive Value; PCRc: PCR consensus results.
95% CI for sensitivity, specificity, PPV and NPV.