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. 2014 Sep 14;20(34):12062–12081. doi: 10.3748/wjg.v20.i34.12062

Figure 1.

Figure 1

Origin of pancreatic ductal adenocarcinoma. It is widely accepted that pancreatic ductal carcinoma (PDAC) arises from precursor lesions derived from ductal cells; however, recently another model has been proposed where PDAC arises from acinar cells through a process called “acinar to ductal metaplasia” (ADM). PanIN: Intraepithelial neoplasm; IPMN: Intraductal papillary mucinous neoplasm; MCN: Mucinous cystic neoplasm.