Table 3.
Meta-analysis of β-catenin expression and clinicopathological features of gastric cancer
| Clinicopathological features | Studies (n) | Cases |
Pooled OR (95%CI) |
P value |
Heterogeneity |
||
| Fixed | Random | I2 (%) | P value | ||||
| Lauren classification | 17 | 1793 | 1.98 (1.19-3.29) | 0.009 | 74 | < 0.00001 | |
| TNM stage | 9 | 996 | 1.34 (0.96-1.86) | 0.080 | 44 | 0.090 | |
| The depth of invasion | 10 | 1203 | 1.48 (0.94-2.33) | 0.090 | 55 | 0.020 | |
| Lymph node metastasis | 16 | 2147 | 2.00 (1.44-2.77) | < 0.0001 | 44 | 0.040 | |
| Distant metastasis | 4 | 258 | 2.69 (1.35-5.38) | 0.005 | 20 | 0.290 | |
| Grade of differentiation | 12 | 1372 | 2.68 (1.66-4.34) | 0.0002 | 58 | 0.006 | |
| Vascular invasion | 3 | 774 | 1.11 (0.70-1.76) | 0.660 | 0 | 0.440 | |
TNM: Tumor-node-metastasis.