Table 2.
Peptide predictions and affinities
| Peptide sequence | NetMHCpanprediction rank | SLA-1*0401 affinity K D(nM) |
|---|---|---|
| CTELKLSDY | 1.00 | 16 |
| GTEKLTITY | 0.80 | 34 |
| SSSFSFGGF | 0.80 | 378 |
| YVFVGTSRY | 0.10 | 325 |
| ASYGAGAGY | 0.05 | 19 |
Peptide sequences selected for affinity analysis based on NetMHCpan prediction ranks and SLA-1*0401 amino acid requirements for binding. The lower the KD value the higher the affinity for binding. Peptides having KD values <500 nM are considered as intermediate affinity ligands whereas a KD value <100 nM represents a high affinity binding peptide ligand.