Table 1.
Characteristics of Study Children and Available Assay Results
| Febrile (Cases; N = 243) | Asymptomatic (Controls; N = 243) | P Valuea | |
|---|---|---|---|
| Mean age in years (SD) | 4.2 (3.0) | 6.2 (3.9) | <.001 |
| Children <5 y (%) | 165 (67.9) | 122 (50.2) | <.001 |
| Mean COI (SD) | 3.3 (1.7) | 2.6 (1.4) | <.001 |
| Geometric mean parasite density (95% CI) | 4742 (3615–6219) | 1120 (911–1378) | <.001 |
| pfcrt K76T | |||
| Genotypingb results available (%) | 240 (98.8) | 214 (88.1) | <.001 |
| Genotypingb and COI results available (%) | 211 (86.8) | 184 (75.7) | .002 |
| pfmdr1 N86Y | |||
| Genotypingb results available (%) | 243 (100.0) | 229 (94.2) | <.001 |
| Genotypingb and COI results available (%) | 214 (88.1) | 194 (79.8) | .013 |
| pfmdr1 D1246Y | |||
| Genotypingb results available (%) | 207 (85.2) | 231 (95.1) | <.001 |
| Genotypingb and COI results available (%) | 182 (74.9) | 195 (80.3) | <.001 |
Abbreviation: COI, complexity of infection.
a P values comparing mean age and COI were based on a 2-sample t test and comparing parasite density on a 2-sample Wilcoxon rank-sum (Mann–Whitney) test. P values for categorical variables were based on the χ2 test.
b Genotyping consisted of characterization of the indicated polymorphism.