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. 2014 Jul;5(7-8):273–284. doi: 10.18632/genesandcancer.25

Table 2. Correlation of C-MYC gene expression with Type I/Type II ERG ratio.

Biological Breakdown Type I/Type II ratio
N Median P
C-MYC fold difference: (45) 0.37 0.063
**0.056
< 0.5 fold (down-regulation) 8 0.28 **
0.5-2 fold (relatively unchanged) 23 0.46
> 2.0 fold (up-regulation) 14 0.72
**

Trending towards significance. P < 0.05 was considered significant.

As C-MYC gene expression is found to be down-regulated in CaP patients, Type I/II ERG ratio is low. When C-MYC gene expression is up-regulated in CaP patients, Type I/II ERG ratio is found to be high.