Structure of Rab11b.
A, stereo image of the superposition of Rab11b (red), Rab11b′ (black), and the previously solved Rab11b-GDP complex (blue) (PDB code 2F9L) (36). B, structural alignment of the PKG II LZ-Rab11b (red) with the previously determined structures of Rab11b bound to GMPPNHP in teal (PDB code 2F9M) and GDP in purple (PDB code 2F9L) (36). The enlarged panel to the right shows a close-up view of the rearrangement of the 310-helix near the switch II region of Rab11b, which places Tyr-73 and Ile-76 in position to make contacts with the PKG II LZ.