FIGURE 3.

Recombinant PKM2 promotes PC-3 tumor growth. A–C, growth of PC-3 tumor under the treatment of different recombinant proteins (indicated, one tumor in the rPKM1 treatment group did not grow) was monitored by the growth curve by measuring tumor volumes every 2 days, and the tumor volumes were calculated by formula tumor volume = π/6 × (width) 2 × length (A), end point pictures (B), and end point weights of the harvested tumors after 13 days of growth with 8 days of treatment (C). The p values are presented by * (p ≤ 0.05) or NS (statistically insignificant; p > 0.05) and were calculated using unpaired two-tailed Student's t test. The error bars in A are S.D. from measurement of five mice.