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Importance of the distance between the N-terminal Arg residue and the tripartite of the lipopolysaccharide-binding site
Relative activities were expressed in percentage terms against the activity of wild-type factor C.
| −3 | −2 | −1 | 1 | 2 | 3 | 4 | 5 | Relative activity | |
|---|---|---|---|---|---|---|---|---|---|
| % | |||||||||
| Wild type | R | G | V | D | L | 100 | |||
| ΔGly2-factor C | R | V | D | L | NDa | ||||
| ΔGly2-Val3-factor C | R | D | L | ND | |||||
| ΔGly2-Val3-Asp4-factor C | R | L | ND | ||||||
| +R-factor C | R | R | G | V | D | L | 30 ± 1.9 | ||
| +RTG-factor C | R | T | G | R | G | V | D | L | ND |
a ND, not detectable.
