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Snf2 family classification schemes. (A) Original subfamilies defined by sequence comparison of Eisen et al using ATPase and flanking sequences [25]. (B) Schematic of subfamilies defined by expanded phylogenomic comparison of Flaus et al using Snf2 family ATPase region [26]. Subfamilies take name and nomenclature from first biochemically identified archetype. (C) Example of an empirical classification of chromatin remodelling enzymes into separate families [10].
