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. 2014 Sep 9;83(11):974–980. doi: 10.1212/WNL.0000000000000775

Figure 2. Cross-sectional comparisons of MRS T2 between corticosteroid-treated and corticosteroid-naive boys with Duchenne muscular dystrophy.

Figure 2

An example gradient echo image of the lower leg with voxel placement in the soleus (Sol) muscle is depicted with the corresponding spectra acquired during the spectroscopic relaxometry scan. (A) Cross-sectional comparisons of T2 by spectroscopy between corticosteroid-treated boys (CS) and corticosteroid-naive boys (CS-naive) with Duchenne muscular dystrophy. (B) T2 values for both the Sol and vastus lateralis (VL) muscles were lower in CS boys compared to CS-naive boys, indicating less damage in the muscles of boys on corticosteroid treatment. Values are represented as mean ± SEM; **p ≤ 0.01 and *p ≤ 0.05. MRS = magnetic resonance spectroscopy; TE = echo time.