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Rough overview of features of placenta-derived toxicological test systems (“workload/n” stands for estimated workload per experiment).
| Exposure time | Availability | Reproducibility | Work load/n | |
|---|---|---|---|---|
| Cell lines | Unlimited | Unlimited | High | Low |
| Placenta explants | A few days | High | Patient-dependent | Low |
| Isolated cells | A few days | limited | Patient-dependent | Medium |
| One side perfusion | 8 hr | 1–2/day | Patient-dependent | Medium |
| Dual perfusion | 8 hr | 3/week | Patient-dependent | High |
