Table 1.

Checklist to maximize the clinical utility of serum AMH testing

1. Use one laboratory, calibrated to outcomes	Avoid ‘mixing and matching’ AMH values from different laboratories and identify a reliable, single source for testing which both calibrates the results to the clinical outcomes of interest and commits to updating the clinician if calibration of the results changes.
2. Utilize more than one ovarian reserve test	Avoid using a single serum AMH measurement alone to assess ovarian reserve, and incorporate other markers such as antral follicle count (AFC) and/or early follicular phase serum FSH.
3. Identify exposures	Identify whether the patient has taken medications (e.g. hormonal contraceptives and chemotherapy) or had surgery (ovarian cyst or endometrioma removal) that affects the AMH levels.
4. Counsel patient	Prior to testing, verify the patient understands the directional nature of the information being provided by AMH testing, and that, in a subset of women, the test result may change substantially with biologic fluctuations.
5. Consider retesting	If testing results lead to life-changing decisions or if the results are inconsistent with the clinical scenario, consider retesting.

Many improvements to the management of women's health are possible through appropriate AMH testing. However, variability in AMH results can lead to clinically significant variability in AMH results, making careful approach to the interpretation essential. With the above simple steps, a clinician can rapidly minimize the risks for incorrect interpretation.

AMH, antimüllerian hormone; FSH, follicle stimulating hormone.