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. 2014 Sep 12;5:348. doi: 10.3389/fphys.2014.00348

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Copyright © 2014 D'hondt, Iyyathurai, Himpens, Leybaert and Bultynck.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structure of the cornea. (A) Schematic representation of the structure of the human cornea: 1. Tear film with (starting from the outermost surface) a lipid layer, aqueous layer and a mucous layer. 2. Epithelial cells. 3. Bowman's membrane. 4. Stroma with keratocytes in an extracellular matrix of collagen fibrils and glycoaminoglycans. 5. Descemet's membrane. 6. Endothelial monolayer. (B) Transverse section of the epithelium and part of the stroma in bovine cornea. (C) Scanning electron microscopy of bovine corneal endothelium. Note the hexagonal shape of the cells. (D) Scanning electron microscopy of a transverse section of bovine cornea showing (from bottom to top) endothelium (6), the two distinct layers of Descemet's membrane (5) and a part of the stroma (4).