Table 1.

Baseline Documentation of Target and Nontarget Lesions

Lesions	Definition	Baseline documentation
Target lesions	RAI-avid areas with the largest dimension of more than or equal to 1 cm by CT scan, and in the case of metastatic lymph nodes as more than or equal to 1.5 cm in short axis when assessed by CT scan	All target lesions up to a maximum of five lesions total and a maximum of two lesions per organ were measured and the sum of the longest diameter (or in case of lymph nodes of the short axis) was recorded.
Nontarget lesions	All other metastatic lesions, lesions which were subjected to additional locoregional treatment such as additional surgery or external beam radiation therapy were also considered nontarget lesions.	All nontarget lesions were recorded at baseline as present, absent, countable, uncountable, or multiple.

Source: Eisenhauer et al. (12).

CT, computed tomography; RAI, radioiodine.