Table 3.
Risk Group* | No. of Patients | % EFS (± SE) |
% OS (± SE) |
||||
---|---|---|---|---|---|---|---|
Year 5 | Year 10 | P | Year 5 | Year 10 | P | ||
Low | |||||||
BCR-ABL1–like | 16 | 100 ± 0.0 | 85.6 ± 14.5 | .36 | 100 ± 0.0 | 100 ± 0.0 | .49 |
Other B-ALL | 179 | 95.0 ± 1.6 | 92.5 ± 4.2 | 98.3 ± 1.0 | 96.2 ± 3.0 | ||
Standard | |||||||
BCR-ABL1–like | 18 | 88.9 ± 7.2 | 83.3 ± 15.2 | .97 | 88.9 ± 7.2 | 83.0 ± 15.3 | .32 |
Other B-ALL | 109 | 84.3 ± 3.6 | 83.3 ± 6.9 | 92.7 ± 2.6 | 91.6 ± 5.0 | ||
High | |||||||
BCR-ABL1–like | 6 | 66.7 ± 17.2 | 66.7 ± 38.5 | .49 | 83.3 ± 13.9 | 83.3 ± 34.0 | .58 |
Other B-ALL | 16 | 41.3 ± 12.0 | 41.3 ± 22.4 | 74.0 ± 10.9 | 64.8 ± 22.2 |
Abbreviations: ALL, acute lymphoblastic leukemia; B-ALL, B-cell ALL; EFS, event-free survival; OS, overall survival.
Based on minimal residual disease levels measured on days 19 and 46 of remission induction.