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. 2014 Sep 12;9(9):e106969. doi: 10.1371/journal.pone.0106969

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© 2014 Nakahara et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Typical EEG, EMG, and LOC of control and reflux esophagitis. (B) Effect of reflux esophagitis on the amount of each stage during the 12-h light period and 12-h dark period. (C) Time course analysis of each stage during a whole day. N = 8. Data are mean ± SEM. White bars and circles represented control rats. Black bars and circles represented reflux esophagitis rats. *p<0.05 versus control. **p<0.01 versus control. EEG, electroencephalograph; EMG, electromyography; LOC, locomotor; NREM, nonrapid eye movement; REM, rapid eye movement.