Table 1. Effects of omeprazole on gastric acid secretion in rats.
9:00 a.m.–3:00 p.m. | 3:00 p.m.–9:00 pm | |||||
Volume (mL/6 h) | pH | Acid output (µEq/6 h) | Volume (mL/6 h) | pH | Acid output (µEq/6 h) | |
Control | 17.4±1.5 | 1.4±0.02 | 1194±124 | 10.8±2.5 | 1.5±0.1 | 897±310 |
Omeprazole | 8.5±0.6* | 6.0±0.1* | 26±17* | 4.4±1.3* | 5.9±0.9* | 40±34* |
Data were mean ± SEM. * p<0.01 versus control.